The Pooling Method – Op. Dr. Ufuk Yılmaz

The Pooling Method

Havuzlama Yöntemi İngilizce adıyla pooling, embriyo transferi olmaksızın iki veya daha çok kez yumurta toplanması ve bu oluşan embriyoların dondurularak daha sonra dondurulmuş siklusa transfer edilmesine denir. Bu yöntem daha çok yumurta rezervi düşük olan veya birkaç kez tüp bebek başarısızlığı olup PGS için yeterli embriyo elde etmek istenen kişilere veya taze transferde başarısız olup dondurulmuş transfer yapılacak hastalara önerilmektedir.

havuzlama (pooling)

The pooling method, also known as ‘pooling’ in English, involves the collection of eggs two or more times without undergoing embryo transfer. The resulting embryos are frozen and later transferred in a frozen cycle. This method is recommended for individuals with low egg reserves, those who have experienced multiple IVF failures but wish to obtain sufficient embryos for PGS (Preimplantation Genetic Screening), or patients who have had unsuccessful fresh transfers and are planning frozen transfers.

What is the Purpose of the Pooling Method?

For the pooling method to succeed, the center must have a reliable vitrification or freezing program. The primary goal of this method is to enhance success per embryo transfer. This is achieved by collecting embryos and thawing them together, then selecting the embryos with the highest potential for implantation when they reach the blastocyst stage on the 5th day. This is a crucial parameter on the path to success. Another objective is to increase the number of embryos to be transferred, thereby further improving the success rate per transfer. Adding genetic analysis to patients who undergo embryo pooling is also necessary. It’s a known fact that genetic issues are more commonly observed in patients with low egg reserves. Obtaining genetically healthy embryos contributes to enhancing the chances of a successful pregnancy.