Blastocyst Transfer – Op. Dr. Ufuk Yılmaz

Blastocyst Transfer

The question ‘What is Blastocyst Transfer?’ can be answered as follows: In the early stages of In Vitro Fertilization (IVF) treatment, embryo transfers were traditionally performed only at the cleavage stage (2nd or 3rd day after fertilization). It was not possible to determine with certainty which of the obtained embryos was more suitable for transfer in terms of the chances of pregnancy at the 3rd day. However, with advancements in laboratory techniques, increased knowledge about embryos, and improvements in the culture solutions used, embryos can now be developed until the blastocyst stage. By waiting for an additional 2 days after the 3rd day, embryos with a higher chance of implantation in the mother’s uterus can be obtained.

However, good-quality embryos can continue developing until the 5th day. Additionally, the likelihood of genetic defects or chromosomal abnormalities in 5-day-old embryos is significantly lower compared to 3-day-old embryos.

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Is it applicable to every patient?

The studies and laboratory results have shown that embryo transfer on the 5th day yields higher pregnancy rates compared to transfers performed on the 2nd or 3rd day. However, blastocyst transfer may not be applicable to every patient. It can be applied to patients who have a large number of good-quality embryos at the cleavage stage.

Patients for Transfer Should Be Carefully Selected

In our laboratory, 70% of embryos reach the blastocyst stage. However, in patients of advanced age or with severe sperm problems, blastocyst development may be reduced, and sometimes no blastocysts can be obtained. In such cases, the embryo transfer is canceled. Therefore, it is important to carefully select patients for blastocyst transfer. Your doctor will provide you with the best options and information regarding this matter.


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